SCHEMBL23657182

SCHEMBL23657182

CNC1CN(CCCOC)C1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.39
HRH2 P25021 1/20 0.39
HRH1 P35367 1/20 0.39
GBA1 P04062 1/20 0.35
HTR4 Q13639 5/20 0.32
CYP3A4 P08684 1/20 0.32
KAT2B Q92831 1/20 0.32
MAPT P10636 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 2/20 0.31
CYP2D6 P10635 1/20 0.31
KCNH2 Q12809 1/20 0.31
GLB1 P16278 1/20 0.31
BRD4 O60885 1/20 0.30
ATAD2 Q6PL18 1/20 0.30
LMNA P02545 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14736595 0.86 GBA1 (0.43) HRH3HRH2HRH1GBA1KAT2B
SCHEMBL25493316 0.79 HRH3 (0.36) HRH3HRH2HRH1CYP3A4MAPT
SCHEMBL20698402 0.75 GBA1 (0.44) HRH3HRH2HRH1GBA1HTR4
SCHEMBL20618418 0.75 GLB1 (0.32) HRH3HRH2HRH1GLB1
SCHEMBL23023305 0.75 GBA1 (0.37) HRH3GBA1HTR4CYP3A4ALDH1A1
SCHEMBL19174517 0.75 EHMT2 (0.38) HRH3GBA1ALDH1A1KDM4EGLB1
SCHEMBL27360642 0.75 CA2 (0.38) HRH3HRH2HRH1GBA1HTR4
SCHEMBL26511273 0.74 OPRM1 (0.35) GBA1CYP3A4
SCHEMBL17286006 0.73 GBA1 (0.36) HRH3HRH2HRH1GBA1HTR4
SCHEMBL18551217 0.73 HRH2 (0.46) HRH3HRH2HRH1GBA1HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021145729-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) 2021-07-22 WO disclosed