Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | TACR2 | P21452 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657349 | 0.91 | HTR1A (0.53) | HRH3HTR1ADRD2DRD3HTR2A | |
| SCHEMBL23657334 | 0.90 | HTR1A (0.52) | HTR1ADRD2DRD3HTR2AKCNH2 | |
| SCHEMBL23657181 | 0.90 | HTR1A (0.55) | HTR1ADRD2DRD3HTR2AKCNH2 | |
| SCHEMBL23657372 | 0.89 | HTR1A (0.54) | HTR1ADRD2DRD3MAPK1KCNH2 | |
| SCHEMBL23657365 | 0.88 | HTR1A (0.50) | HRH3HTR1ADRD2DRD3HTR2A | |
| SCHEMBL23657211 | 0.87 | HTR1A (0.50) | HRH3HTR1ADRD2DRD3HTR2A | |
| SCHEMBL23657180 | 0.87 | HTR1A (0.51) | HTR1ADRD2DRD3KCNH2ACHE | |
| SCHEMBL23657413 | 0.86 | HTR1A (0.52) | HTR1ADRD2DRD3HTR2AKCNH2 | |
| SCHEMBL23657408 | 0.85 | HTR1A (0.53) | HTR1ADRD2DRD3HTR2AKCNH2 | |
| SCHEMBL23657358 | 0.82 | KCNA5 (0.60) | HTR1AHTR2AALDH1A1KCNH2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |