Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657162 | 0.98 | KCNA5 (0.58) | KCNA5KCNH2HTR1AMAPTIDO1 | |
| SCHEMBL23657266 | 0.94 | KCNA5 (0.64) | KCNA5KCNH2HTR1AMAPTHTR1D | |
| SCHEMBL23657311 | 0.90 | KCNA5 (0.48) | KCNA5KCNH2HTR1AMAPTIDO1 | |
| SCHEMBL23657351 | 0.90 | HTR1A (0.53) | KCNA5KCNH2HTR1AMAPTIDO1 | |
| SCHEMBL23657177 | 0.89 | SLC6A4 (0.55) | KCNA5KCNH2HTR1AMAPTIDO1 | |
| SCHEMBL23657359 | 0.89 | SLC6A4 (0.58) | KCNA5KCNH2HTR1AMAPTIDO1 | |
| SCHEMBL23657278 | 0.89 | KCNA5 (0.48) | KCNA5KCNH2HTR1AMAPTIDO1 | |
| SCHEMBL23657372 | 0.86 | HTR1A (0.54) | KCNA5KCNH2HTR1AACHE | |
| SCHEMBL23657413 | 0.85 | HTR1A (0.52) | KCNA5KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL23657181 | 0.85 | HTR1A (0.55) | KCNA5KCNH2HTR1ASLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |