Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809941 | 0.89 | L3MBTL4 (0.56) | L3MBTL4L3MBTL3L3MBTL1ALDH1A1HTT | |
| SCHEMBL2366320 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HTTPKMKMT2AMEN1 | |
| SCHEMBL1806568 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HTTPKMKMT2AMEN1 | |
| SCHEMBL1806520 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HTTPKMKMT2ANAMPT | |
| SCHEMBL12751719 | 0.78 | L3MBTL4 (0.69) | L3MBTL4L3MBTL3L3MBTL1ALDH1A1HTT | |
| SCHEMBL12753258 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HTTPKMKMT2AMEN1 | |
| SCHEMBL1811303 | 0.76 | MGLL (0.57) | ALDH1A1HTTPKMKMT2APOLB | |
| SCHEMBL12752422 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HTTPKMKMT2AMEN1 | |
| SCHEMBL1809258 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HTTPKMNAMPT | |
| SCHEMBL1807182 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HTTPKMNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364975-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-09-14 | — | — | EP | disclosed |