Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657419 | 0.91 | HTR1A (0.59) | HTR1ASLC6A2SLC6A4SLC6A3HTR1D | |
| SCHEMBL23657417 | 0.90 | HTR1A (0.55) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23657295 | 0.90 | HTR1A (0.47) | HTR1ASLC6A4HTR1DHTR1BPRKAB2 | |
| SCHEMBL23657334 | 0.88 | HTR1A (0.52) | HTR1ASLC6A4HTR1DHTR1B | |
| SCHEMBL23657437 | 0.87 | HTR1A (0.44) | HTR1ASLC6A4HTR1DHTR1BADRA1A | |
| SCHEMBL23657455 | 0.87 | PRKAB2 (0.51) | HTR1AHTR1DHTR1BADRA2AADRA2B | |
| SCHEMBL23657407 | 0.87 | HTR1A (0.45) | HTR1AHTR1DHTR1BPRKAB2PRKAG1 | |
| SCHEMBL23657454 | 0.85 | HTR1A (0.46) | HTR1ASLC6A4HTR1DHTR1BPRKAB2 | |
| SCHEMBL23657409 | 0.84 | SLC6A4 (0.46) | HTR1ASLC6A2SLC6A4SLC6A3HTR1D | |
| SCHEMBL23648935 | 0.83 | HTR1A (0.53) | HTR1ASLC6A2SLC6A4SLC6A3HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |