Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657295 | 0.97 | HTR1A (0.47) | HTR1AHTR1DHTR1BPRKAB2PRKAG1 | |
| SCHEMBL23657377 | 0.93 | HTR1A (0.49) | HTR1AHTR1DHTR1BHRH3MPO | |
| SCHEMBL23657431 | 0.93 | HTR1A (0.48) | HTR1AHTR1DHTR1BHRH3MPO | |
| SCHEMBL23657284 | 0.93 | HTR1A (0.48) | HTR1AHTR1DHTR1BHRH3MPO | |
| SCHEMBL23657454 | 0.93 | HTR1A (0.46) | HTR1AHTR1DHTR1BPRKAB2PRKAG1 | |
| SCHEMBL23657427 | 0.89 | HTR1A (0.49) | HTR1AHTR1DHTR1BMPOHTR2A | |
| SCHEMBL23657430 | 0.88 | MPO (0.42) | HTR1AHTR1DHTR1BMPOGFER | |
| SCHEMBL23657405 | 0.88 | HTR1A (0.51) | HTR1AHTR1DHTR1BMPOGFER | |
| SCHEMBL23657373 | 0.88 | HTR1A (0.44) | HTR1AHTR1DHTR1BGFERHSD17B10 | |
| SCHEMBL23657455 | 0.88 | PRKAB2 (0.51) | HTR1AHTR1DHTR1BHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |