SCHEMBL23657359

SCHEMBL23657359

CN(C)CCCOc1ccc(SNCCCc2c[nH]c3ccccc23)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.58
HTR1A P08908 8/20 0.51
HTR2A P28223 2/20 0.51
HTR2C P28335 2/20 0.51
HTR2B P41595 2/20 0.51
KCNA5 P22460 1/20 0.48
KCNH2 Q12809 1/20 0.48
HTR1B P28222 2/20 0.45
HTR1D P28221 2/20 0.45
IDO1 P14902 1/20 0.45
ACHE P22303 2/20 0.44
BCHE P06276 1/20 0.44
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
MAOA P21397 1/20 0.43
ADRA1D P25100 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
HTR7 P34969 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23657177 0.96 SLC6A4 (0.55) SLC6A4HTR1AHTR2AHTR2CHTR2B
SCHEMBL23657351 0.90 HTR1A (0.53) SLC6A4HTR1AHTR2AKCNA5KCNH2
SCHEMBL23657358 0.89 KCNA5 (0.60) SLC6A4HTR1AHTR2AKCNA5KCNH2
SCHEMBL23657162 0.88 KCNA5 (0.58) SLC6A4HTR1AHTR2AKCNA5KCNH2
SCHEMBL23657311 0.86 KCNA5 (0.48) SLC6A4HTR1AHTR2AKCNA5KCNH2
SCHEMBL23657278 0.86 KCNA5 (0.48) SLC6A4HTR1AHTR2AKCNA5KCNH2
SCHEMBL23657266 0.84 KCNA5 (0.64) HTR1AHTR2AKCNA5KCNH2HTR1B
SCHEMBL23657413 0.82 HTR1A (0.52) HTR1AHTR2AKCNA5KCNH2HTR1B
SCHEMBL23657181 0.82 HTR1A (0.55) SLC6A4HTR1AHTR2AKCNA5KCNH2
SCHEMBL29824458 0.80 KCNA5 (0.73) SLC6A4HTR1AKCNA5KCNH2HTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021145729-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) 2021-07-22 WO disclosed