SCHEMBL23657405

SCHEMBL23657405

CN1CCN(CCCOc2ccc(SNCCCc3c[nH]c4ccc(Cl)cc34)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 10/20 0.51
MPO P05164 1/20 0.49
HTR1D P28221 3/20 0.46
HTR1B P28222 3/20 0.46
HTR6 P50406 1/20 0.46
KCNH2 Q12809 1/20 0.46
HRH4 Q9H3N8 1/20 0.45
GFER P55789 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23657427 0.97 HTR1A (0.49) HTR1AMPOHTR1DHTR1BHTR6
SCHEMBL23657456 0.96 HTR1A (0.50) HTR1AMPOHTR1DHTR1BHTR6
SCHEMBL23657377 0.93 HTR1A (0.49) HTR1AMPOHTR1DHTR1BHTR6
SCHEMBL23657431 0.92 HTR1A (0.48) HTR1AMPOHTR1DHTR1B
SCHEMBL23657284 0.92 HTR1A (0.48) HTR1AMPOHTR1DHTR1B
SCHEMBL23657295 0.91 HTR1A (0.47) HTR1AHTR1DHTR1BHTR6KCNH2
SCHEMBL23657325 0.90 PRKAB2 (0.51) HTR1AMPOHTR1DHTR1B
SCHEMBL23657420 0.90 HTR1A (0.64) HTR1A
SCHEMBL23657396 0.90 HTR1A (0.51) HTR1AMPOHTR1DHTR1B
SCHEMBL23657268 0.90 HTR1A (0.46) HTR1AHTR1DHTR1BHTR6KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021145729-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) 2021-07-22 WO disclosed