Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.51 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | HTR1D | P28221 | 3/20 | 0.47 |
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657420 | 0.91 | HTR1A (0.64) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL23657283 | 0.90 | MPO (0.64) | HTR1AMPO | |
| SCHEMBL23657419 | 0.90 | HTR1A (0.59) | HTR1AMPOHTR1DHTR1BADRA2A | |
| SCHEMBL23657405 | 0.90 | HTR1A (0.51) | HTR1AMPOHTR1DHTR1B | |
| SCHEMBL23657181 | 0.88 | HTR1A (0.55) | HTR1AMPODRD2 | |
| SCHEMBL23657313 | 0.88 | RAB9A (0.52) | HTR1AMPOHTR1DHTR1B | |
| SCHEMBL23657325 | 0.88 | PRKAB2 (0.51) | HTR1AMPOHTR1DHTR1BADRA2A | |
| SCHEMBL23657427 | 0.88 | HTR1A (0.49) | HTR1AMPOHTR1DHTR1B | |
| SCHEMBL23657418 | 0.87 | HTR1A (0.62) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL23657456 | 0.86 | HTR1A (0.50) | HTR1AMPOHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |