Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.75 |
| ▸ | TP53 | P04637 | 8/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | LMNA | P02545 | 8/20 | 0.73 |
| ▸ | RAB9A | P51151 | 9/20 | 0.72 |
| ▸ | NPC1 | O15118 | 8/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | GFER | P55789 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CLK1 | P49759 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14807083 | 0.86 | RAB9A (0.75) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14654072 | 0.83 | RAB9A (0.71) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14631274 | 0.83 | MAPT (0.71) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3109465 | 0.83 | NPC1 (0.77) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16562034 | 0.81 | ALDH1A1 (0.79) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17916670 | 0.79 | NPC1 (0.65) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17916714 | 0.79 | ALDH1A1 (0.75) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3167505 | 0.78 | MAPT (0.53) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14631511 | 0.77 | RAB9A (0.62) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3384688 | 0.75 | MAPT (0.70) | MAPTTP53SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | MAPT 4875/4885TP53 1313/4885SMN1; SMN2 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.