Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376366 | 0.85 | SMN1; SMN2 (0.49) | KMT2AMEN1NPC1CYP2C19SMN1; SMN2 | |
| SCHEMBL17868152 | 0.84 | KMT2A (0.52) | POLBALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7233616 | 0.83 | HPGD (0.46) | POLBALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL27606506 | 0.82 | MAPT (0.43) | POLBALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL2127522 | 0.81 | MAPT (0.44) | ALDH1A1KMT2AMEN1NPC1HPGD | |
| SCHEMBL159259 | 0.81 | L3MBTL1 (0.54) | ALDH1A1KMT2AMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1000168 | 0.80 | L3MBTL1 (0.53) | ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL275384 | 0.79 | KDM4E (0.50) | POLBALDH1A1KMT2AMEN1CYP2D6 | |
| SCHEMBL10654584 | 0.79 | MAPT (0.46) | POLBALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL16903362 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1KMT2AMEN1NPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230100186-A1 | FENTANYL HAPTENS FOR THE PREPARATION OF A FENTANYL VACCINE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2023-03-30 | — | — | US | disclosed |
| WO-2021146334-A1 | FENTANYL HAPTENS FOR THE PREPARATION OF A FENTANYL VACCINE | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2021-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230100186-A1 | FENTANYL HAPTENS FOR THE PREPARATION OF A FENTANYL VACCINE | OPRL1, OPRK1, CYP2F1 | POLB 3830/4885ALDH1A1 1790/4885KMT2A 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.