Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24015935 | 0.73 | ACACB (0.42) | ACACB | |
| SCHEMBL17707572 | 0.71 | HDAC6 (0.67) | L3MBTL1 | |
| SCHEMBL7603560 | 0.71 | CYP3A4 (0.38) | L3MBTL1 | |
| SCHEMBL13798845 | 0.71 | — | — | |
| SCHEMBL10061707 | 0.69 | ALDH1A1 (0.54) | ACACBL3MBTL1MAPK1ACACA | |
| SCHEMBL13647285 | 0.68 | TAAR1 (0.53) | — | |
| SCHEMBL7736420 | 0.68 | KMT2A (0.51) | ACACBL3MBTL1MAPK1ACACA | |
| SCHEMBL2325957 | 0.68 | TAAR1 (0.41) | — | |
| SCHEMBL7266543 | 0.67 | LMNA (0.43) | — | |
| SCHEMBL7266548 | 0.67 | LMNA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021146629-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS | NUVATION BIO INC. (US) | 2021-07-22 | — | — | WO | disclosed |