Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23666641 | 0.71 | ACACB (0.41) | L3MBTL1 | |
| SCHEMBL356020 | 0.67 | LMNA (0.47) | CYP3A4KMT2AGAAALDH1A1LMNA | |
| SCHEMBL3416651 | 0.67 | POLB (0.48) | CYP3A4GAALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL6274860 | 0.67 | CYP3A4 (0.44) | CYP3A4CYP2C9KMT2ATAAR1GAA | |
| SCHEMBL28421004 | 0.67 | KMT2A (0.50) | KMT2AGAAALDH1A1MAPTMEN1 | |
| SCHEMBL4743135 | 0.66 | CYP3A4 (0.43) | CYP3A4CYP2C9KMT2ATAAR1GAA | |
| SCHEMBL22836908 | 0.65 | TAAR1 (0.32) | CYP3A4CYP2C9KMT2ATAAR1 | |
| Hydrochloric Acid SCHEMBL27891676 | 0.65 | LMNA (0.46) | CYP3A4KMT2AGAAALDH1A1LMNA | |
| Methyl Alcohol SCHEMBL28233463 | 0.65 | LMNA (0.46) | CYP3A4KMT2AGAAALDH1A1LMNA | |
| SCHEMBL1802391 | 0.65 | KMT2A (0.39) | CYP3A4CYP2C9KMT2ATAAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263711-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062704-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | disclosed |