SCHEMBL2367247

CCCC[C@H](NC(=O)[C@@H](N)[C@H](O)C(C)C)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](COC(=O)C(F)(F)F)C(=O)O)[C@H](C)OC(=O)C(F)(F)F)[C@@H](C)CC

nearest known ligand 0.39

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	RXFP1	Q9HBX9	6/20	0.39

▸	NPY4R	P50391	1/20	0.32

▸	PRSS1	P07477	1/20	0.32

▸	FURIN	P09958	1/20	0.32

▸	ECE1	P42892	1/20	0.32

▸	GLP1R	P43220	1/20	0.32

▸	MUS81	Q96NY9	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2367390	0.97	RXFP1 (0.38)	RXFP1NPY4R
SCHEMBL2367050	0.95	RXFP1 (0.42)	RXFP1NPY4R
SCHEMBL2367433	0.91	NPY4R (0.40)	RXFP1NPY4RPRSS1FURIN
SCHEMBL2367400	0.90	RXFP1 (0.40)	RXFP1NPY4R
SCHEMBL2367032	0.90	RXFP1 (0.40)	RXFP1NPY4R
SCHEMBL2367328	0.89	RXFP1 (0.41)	RXFP1NPY4R
SCHEMBL2366970	0.89	RXFP1 (0.41)	RXFP1NPY4R
SCHEMBL2367832	0.88	RXFP1 (0.37)	RXFP1NPY4R
SCHEMBL2367412	0.87	RXFP1 (0.39)	RXFP1NPY4RPRSS1FURIN
SCHEMBL5073480	0.86	NPY4R (0.47)	NPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2007794-B1	LYSOBACTIN AMIDES	AICURIS GMBH & CO KG (DE)	2011-09-14	—	—	EP	disclosed