Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 8/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 4/20 | 0.42 |
| ▸ | NPY2R | P49146 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.42 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | VIPR1 | P32241 | 1/20 | 0.41 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367775 | 0.93 | CTSB (0.43) | NPY4RKEAP1VIPR1VIPR2 | |
| SCHEMBL2367433 | 0.93 | NPY4R (0.40) | NPY4RKEAP1NPY1RNPY2RNPY5R | |
| SCHEMBL2367328 | 0.91 | RXFP1 (0.41) | NPY4RKEAP1VIPR1VIPR2 | |
| SCHEMBL2366970 | 0.91 | RXFP1 (0.41) | NPY4RKEAP1VIPR1VIPR2 | |
| SCHEMBL2367050 | 0.91 | RXFP1 (0.42) | NPY4RNPY1RNPY5RSLC2A1VIPR1 | |
| SCHEMBL2367032 | 0.91 | RXFP1 (0.40) | NPY4RKEAP1VIPR1VIPR2 | |
| SCHEMBL2367400 | 0.91 | RXFP1 (0.40) | NPY4RKEAP1VIPR1VIPR2 | |
| SCHEMBL2373308 | 0.90 | NPY4R (0.50) | NPY4RKEAP1NPY1RNPY2RNPY5R | |
| SCHEMBL2368042 | 0.88 | RXFP1 (0.44) | NPY4RKEAP1CTSDNPY1RNPY2R | |
| SCHEMBL2366814 | 0.88 | RXFP1 (0.42) | NPY4RKEAP1NPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-A1 | LYSOBACTIN AMIDES | AiCuris GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |