Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367121 | 1.00 | CETP (0.46) | CETPCSNK1ECNR2CTRCCTSK | |
| SCHEMBL9498100 | 0.98 | CETP (0.43) | CETPCSNK1ECNR2CTSKCTSL | |
| SCHEMBL10452494 | 0.94 | CTSK (0.45) | CETPCNR2CTSKCTSLCTSB | |
| SCHEMBL28428539 | 0.87 | SLC1A3 (0.42) | CETPCTSKCTSLCTSBCTSH | |
| SCHEMBL31518969 | 0.87 | SLC1A3 (0.42) | CETPCTSKCTSLCTSBCTSH | |
| SCHEMBL6678199 | 0.85 | CETP (0.42) | CETPCSNK1ECNR2CTRC | |
| SCHEMBL11733830 | 0.83 | CETP (0.40) | CETPCSNK1ECNR2CTRC | |
| SCHEMBL6675434 | 0.83 | CETP (0.40) | CETPCSNK1ECNR2CTRC | |
| SCHEMBL24340394 | 0.83 | TLR2 (0.42) | CETP | |
| SCHEMBL10494267 | 0.83 | TLR2 (0.42) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11414393-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-08-16 | — | — | US | disclosed |
| US-20210101875-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-08 | — | — | US | disclosed |
| US-10844028-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190177289-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-06-13 | — | — | US | disclosed |
| US-10189802-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-29 | — | — | US | disclosed |
| EP-3269395-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | Massachusetts Institute Of Technology (US) | 2018-01-17 | — | — | EP | disclosed |
| US-20170204075-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-20 | — | — | US | disclosed |
| EP-2365962-B1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2017-07-05 | — | — | EP | disclosed |
| US-9556110-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150203439-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2015-07-23 | — | — | US | disclosed |
| US-8969353-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-03-03 | — | — | US | disclosed |
| US-8450298-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20110293703-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-12-01 | — | — | US | disclosed |
| EP-2365962-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2011-09-21 | — | — | EP | disclosed |
| US-20100331234-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-30 | — | — | US | disclosed |
| WO-2010053572-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203439-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | CETP 61/4885CSNK1E 3634/4885CNR2 1575/4885 |
| US-20110293703-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | CETP 61/4885CSNK1E 3634/4885CNR2 1575/4885 |
| US-11414393-B2 | Aminoalcohol lipidoids and uses thereof | PHOSPHO1, PNMT, AASDHPPT | CETP 61/4885CSNK1E 3634/4885CNR2 1575/4885 |
| US-20190177289-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | CETP 61/4885CSNK1E 3634/4885CNR2 1575/4885 |
| US-20210101875-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | CETP 61/4885CSNK1E 3634/4885CNR2 1575/4885 |
| US-20170204075-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | CETP 61/4885CSNK1E 3634/4885CNR2 1575/4885 |
| US-20100331234-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | CETP 61/4885CSNK1E 3634/4885CNR2 1575/4885 |
| US-10844028-B2 | Aminoalcohol lipidoids and uses thereof | PHOSPHO1, PNMT, AASDHPPT | CETP 61/4885CSNK1E 3634/4885CNR2 1575/4885 |
| US-10189802-B2 | Aminoalcohol lipidoids and uses thereof | PHOSPHO1, PNMT, AASDHPPT | CETP 61/4885CSNK1E 3634/4885CNR2 1575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.