Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 4/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367746 | 1.00 | KMT2A (0.46) | KMT2AMEN1L3MBTL1SYKCA1 | |
| SCHEMBL4082634 | 0.95 | KMT2A (0.46) | KMT2AMEN1L3MBTL1SYKCA1 | |
| SCHEMBL4082629 | 0.95 | KMT2A (0.46) | KMT2AMEN1L3MBTL1SYKCA1 | |
| SCHEMBL2367119 | 0.86 | MGLL (0.45) | KMT2AMEN1SYKSMN1; SMN2BACE1 | |
| SCHEMBL27745756 | 0.82 | KLK5 (0.51) | KMT2AMEN1L3MBTL1SYKITGA4 | |
| SCHEMBL2367000 | 0.82 | KLK5 (0.51) | KMT2AMEN1L3MBTL1SYKITGA4 | |
| SCHEMBL4082106 | 0.80 | ALDH1A1 (0.53) | KMT2AMEN1SYKITGA4ITGB7 | |
| SCHEMBL4082673 | 0.80 | ALDH1A1 (0.53) | KMT2AMEN1SYKITGA4ITGB7 | |
| SCHEMBL4089152 | 0.80 | ALDH1A1 (0.53) | KMT2AMEN1SYKITGA4ITGB7 | |
| SCHEMBL3045973 | 0.79 | MGLL (0.46) | KMT2AMEN1SYKSMN1; SMN2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |