Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 4/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082634 | 1.00 | KMT2A (0.46) | KMT2AMEN1L3MBTL1SYKCA1 | |
| SCHEMBL2367746 | 0.95 | KMT2A (0.46) | KMT2AMEN1L3MBTL1SYKCA1 | |
| SCHEMBL2367173 | 0.95 | KMT2A (0.46) | KMT2AMEN1L3MBTL1SYKCA1 | |
| SCHEMBL3045978 | 0.85 | MGLL (0.46) | KMT2AMEN1SYKSMN1; SMN2BACE1 | |
| SCHEMBL3045973 | 0.85 | MGLL (0.46) | KMT2AMEN1SYKSMN1; SMN2BACE1 | |
| SCHEMBL4089152 | 0.82 | ALDH1A1 (0.53) | KMT2AMEN1SYKALDH1A1ALOX15 | |
| SCHEMBL4082673 | 0.82 | ALDH1A1 (0.53) | KMT2AMEN1SYKALDH1A1ALOX15 | |
| SCHEMBL4082106 | 0.82 | ALDH1A1 (0.53) | KMT2AMEN1SYKALDH1A1ALOX15 | |
| SCHEMBL2367119 | 0.80 | MGLL (0.45) | KMT2AMEN1SYKSMN1; SMN2PPARG | |
| SCHEMBL2367000 | 0.80 | KLK5 (0.51) | KMT2AMEN1L3MBTL1SYKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076285-B2 | Lysobactin amides | AICURIS GMBH & CO. KG (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20090203582-A1 | LYSOBACTIN AMIDES | BAYER HEALTHCARE AG (DE) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203582-A1 | LYSOBACTIN AMIDES | AADAT, HAMP, DLST | KMT2A 448/4885MEN1 2317/4885L3MBTL1 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.