Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 14/20 | 0.67 |
| ▸ | PLG | P00747 | 8/20 | 0.66 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.66 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.66 |
| ▸ | F2 | P00734 | 6/20 | 0.66 |
| ▸ | PLAT | P00750 | 6/20 | 0.66 |
| ▸ | KLK1 | P06870 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28324321 | 0.87 | PLAU (0.56) | PLAUPLGKLKB1PRSS1F2 | |
| 4-Guanidino-Benzoic Acid SCHEMBL9304265 | 0.82 | MEN1 (0.56) | PLAUPLGKLKB1PRSS1F2 | |
| 4-Guanidino-Benzoic Acid SCHEMBL211005 | 0.82 | F2 (0.57) | PRSS1F2TP53NR1H4 | |
| SCHEMBL7335930 | 0.80 | PLAU (0.78) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL9303344 | 0.80 | PLAU (0.74) | PLAUPLGKLKB1PRSS1F2 | |
| 4-Guanidino-Benzoic Acid SCHEMBL273175 | 0.80 | F2 (0.55) | PRSS1F2TP53NR1H4 | |
| 4-Guanidino-Benzoic Acid SCHEMBL10674543 | 0.80 | F2 (0.55) | PRSS1F2TP53NR1H4 | |
| 4-Guanidino-Benzoic Acid SCHEMBL11123754 | 0.80 | F2 (0.55) | PRSS1F2TP53NR1H4 | |
| 4-Guanidino-Benzoic Acid SCHEMBL22127093 | 0.80 | F2 (0.55) | PRSS1F2TP53NR1H4 | |
| Nafamostat SCHEMBL7051240 | 0.80 | PLAU (0.58) | PLAUPLGKLKB1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210807-A1 | USE OF BENZOATE COMPOUND IN TREATMENT OF SARS-COV-2 INFECTIONS | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2023-07-06 | — | — | US | disclosed |
| WO-2021147272-A1 | USE OF BENZOATE COMPOUND IN TREATMENT OF SARS-COV-2 INFECTIONS | 中国人民解放军军事科学院军事医学研究院 | 2021-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210807-A1 | USE OF BENZOATE COMPOUND IN TREATMENT OF SARS-COV-2 INFECTIONS | ACE2, ACE, TMPRSS2 | PLAU 2019/4885PLG 908/4885KLKB1 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.