Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.47 |
| ▸ | BCL6 | P41182 | 4/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100780 | 0.93 | KIF11 (0.48) | KIF11BCL6TNIKCRBNULK1 | |
| SCHEMBL26086593 | 0.93 | KIF11 (0.48) | KIF11BCL6TNIKCRBNULK1 | |
| SCHEMBL26089507 | 0.84 | KIF11 (0.50) | KIF11TNIKCRBNULK1MAPT | |
| SCHEMBL23674979 | 0.82 | KIF11 (0.53) | KIF11TNIKCRBNULK1 | |
| SCHEMBL30100766 | 0.82 | KIF11 (0.53) | KIF11TNIKCRBNULK1 | |
| SCHEMBL23674869 | 0.79 | BCL6 (0.50) | KIF11BCL6TNIKCRBNULK1 | |
| SCHEMBL23674945 | 0.78 | KIF11 (0.51) | KIF11TNIKCRBNULK1MAPT | |
| SCHEMBL30100724 | 0.78 | KIF11 (0.51) | KIF11TNIKCRBNULK1MAPT | |
| SCHEMBL26448666 | 0.77 | MAPT (0.36) | KIF11BCL6CRBNMAPT | |
| SCHEMBL26089226 | 0.76 | MAPT (0.42) | BCL6TNIKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128402-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-04-27 | — | — | US | disclosed |
| US-20230128402-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-04-27 | — | — | US | disclosed |
| WO-2021151062-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | THE TRUSTEES OF PRINCETON UNIVERISTY (US) | 2021-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128402-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PAH, ALDH2, IDH2 | KIF11 3560/4885BCL6 1730/4885TNIK 2690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.