Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.48 |
| ▸ | BCL6 | P41182 | 4/20 | 0.48 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26086593 | 1.00 | KIF11 (0.48) | KIF11BCL6TNIKCRBNULK1 | |
| SCHEMBL23674829 | 0.93 | KIF11 (0.47) | KIF11BCL6TNIKCRBNULK1 | |
| SCHEMBL30100724 | 0.83 | KIF11 (0.51) | KIF11TNIKCRBNULK1PKM | |
| SCHEMBL23674945 | 0.83 | KIF11 (0.51) | KIF11TNIKCRBNULK1PKM | |
| SCHEMBL30100766 | 0.83 | KIF11 (0.53) | KIF11TNIKCRBNULK1PKM | |
| SCHEMBL23674979 | 0.83 | KIF11 (0.53) | KIF11TNIKCRBNULK1PKM | |
| SCHEMBL23674869 | 0.80 | BCL6 (0.50) | KIF11BCL6TNIKCRBNULK1 | |
| SCHEMBL26089507 | 0.78 | KIF11 (0.50) | KIF11TNIKCRBNULK1PKM | |
| SCHEMBL2015376 | 0.77 | NPC1 (0.50) | KIF11CRBNPKM | |
| SCHEMBL30100790 | 0.77 | NPC1 (0.50) | KIF11CRBNPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093400-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | The Trustees of Princeton University (US) | 2022-11-30 | — | — | EP | disclosed |