Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.50 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | ULK1 | O75385 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23674945 | 0.92 | KIF11 (0.51) | KIF11TNIKPKMCRBNULK1 | |
| SCHEMBL30100724 | 0.92 | KIF11 (0.51) | KIF11TNIKPKMCRBNULK1 | |
| SCHEMBL30100766 | 0.85 | KIF11 (0.53) | KIF11TNIKPKMCRBNULK1 | |
| SCHEMBL23674979 | 0.85 | KIF11 (0.53) | KIF11TNIKPKMCRBNULK1 | |
| SCHEMBL23674829 | 0.84 | KIF11 (0.47) | KIF11TNIKCRBNULK1MAPT | |
| SCHEMBL26089273 | 0.81 | KIF11 (0.53) | KIF11TNIKPKMCRBNULK1 | |
| SCHEMBL26086593 | 0.78 | KIF11 (0.48) | KIF11TNIKPKMCRBNULK1 | |
| SCHEMBL30100780 | 0.78 | KIF11 (0.48) | KIF11TNIKPKMCRBNULK1 | |
| SCHEMBL29746163 | 0.78 | MAPT (0.58) | KIF11PKMALDH1A1NPC1MAPT | |
| SCHEMBL26613480 | 0.78 | MAPT (0.58) | KIF11PKMALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128402-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-04-27 | — | — | US | disclosed |
| US-20230128402-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128402-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PAH, ALDH2, IDH2 | KIF11 3560/4885TNIK 2690/4885PKM 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.