Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.55 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 3/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100395 | 0.90 | ERCC1 (0.59) | P2RX1TMPRSS4CDK1P2RX4P2RX7 | |
| SCHEMBL23675382 | 0.90 | ERCC1 (0.59) | P2RX1TMPRSS4CDK1P2RX4P2RX7 | |
| SCHEMBL23675392 | 0.90 | TAS1R3 (0.62) | P2RX1TAS1R3TAS1R1TAS1R2TMPRSS4 | |
| SCHEMBL6357645 | 0.89 | ALDH1A1 (0.53) | P2RX7MEN1KMT2ALMNAMAPT | |
| SCHEMBL23675403 | 0.84 | EPHX2 (0.55) | P2RX1TMPRSS4CDK1P2RX4P2RX7 | |
| SCHEMBL13812639 | 0.82 | P2RX1 (0.66) | P2RX1TAS1R3TAS1R1TAS1R2TMPRSS4 | |
| SCHEMBL23675419 | 0.80 | NPC1 (0.65) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL13812915 | 0.80 | P2RX1 (0.70) | P2RX1TAS1R3TAS1R1TAS1R2TMPRSS4 | |
| SCHEMBL6357659 | 0.80 | TP53 (0.56) | P2RX7MEN1KMT2AROCK2ROCK1 | |
| SCHEMBL6357851 | 0.78 | CNR1 (0.55) | TAS1R3TAS1R1TAS1R2P2RX7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIV OF TEXAS SY (US) | 2023-05-04 | — | — | US | disclosed |
| EP-4093401-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | The Board of Regents of the University of Texas System (US) | 2022-11-30 | — | — | EP | disclosed |
| WO-2021151104-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | EIF2AK2, SARS1, ACE | P2RX1 3088/4885TAS1R3 2667/4885TAS1R1 3039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.