Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 3/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 3/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23675382 | 0.90 | ERCC1 (0.59) | EPHX2CDK1P2RX1TMPRSS4ERCC1 | |
| SCHEMBL30100395 | 0.90 | ERCC1 (0.59) | EPHX2CDK1P2RX1TMPRSS4ERCC1 | |
| SCHEMBL23675437 | 0.84 | P2RX1 (0.56) | EPHX2CDK1P2RX1TMPRSS4ERCC1 | |
| SCHEMBL23675419 | 0.80 | NPC1 (0.65) | P2RX1TMPRSS4LMNAMAPK1TSHR | |
| SCHEMBL29335953 | 0.78 | LMNA (0.71) | EPHX2NR1H4LMNAMAPK1NLRP1 | |
| SCHEMBL29617476 | 0.78 | KCNMA1 (0.68) | P2RX1TMPRSS4LMNAMAPK1TSHR | |
| SCHEMBL11887644 | 0.78 | KCNMA1 (0.68) | P2RX1TMPRSS4LMNAMAPK1TSHR | |
| SCHEMBL26096321 | 0.77 | ALDH1A1 (0.48) | EPHX2NR1H4CDK1P2RX1TMPRSS4 | |
| SCHEMBL23675392 | 0.76 | TAS1R3 (0.62) | CDK1P2RX1TMPRSS4ERCC1ERCC4 | |
| SCHEMBL23675446 | 0.76 | TUBB (0.72) | CDK1P2RX1TMPRSS4ERCC1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIV OF TEXAS SY (US) | 2023-05-04 | — | — | US | disclosed |
| EP-4093401-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | The Board of Regents of the University of Texas System (US) | 2022-11-30 | — | — | EP | disclosed |
| WO-2021151104-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | EIF2AK2, SARS1, ACE | EPHX2 2573/4885NR1H4 4072/4885CDK1 3435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.