SCHEMBL2367658

SCHEMBL2367658

O=C(Oc1csnn1)c1ccccc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.51
HSD17B10 Q99714 4/20 0.51
ALOX15 P16050 1/20 0.51
ALDH1A1 P00352 7/20 0.47
KDM4E B2RXH2 6/20 0.47
TSHR P16473 2/20 0.46
LMNA P02545 1/20 0.46
KMT2A Q03164 5/20 0.45
MAPT P10636 3/20 0.45
TDP1 Q9NUW8 2/20 0.42
GAA P10253 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
RAB9A P51151 2/20 0.39
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
HMGB1 P09429 1/20 0.39
CA4 P22748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3242462 0.73 ALDH1A1 (0.38) HPGDALDH1A1KDM4ELMNAKMT2A
SCHEMBL3908136 0.71 LMNA (0.68) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL29525350 0.71 LMNA (0.68) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL7614991 0.70 HPGD (0.88) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL3635482 0.69 HPGD (0.76) HPGDHSD17B10ALOX15ALDH1A1KDM4E
Phenyl Salicylate SCHEMBL24326 0.69 HPGD (1.00) HPGDHSD17B10ALOX15ALDH1A1KDM4E
Phenyl Salicylate SCHEMBL2519840 0.69 HPGD (1.00) HPGDHSD17B10ALOX15ALDH1A1KDM4E
Phenyl Salicylate SCHEMBL29625250 0.69 HPGD (1.00) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL4461056 0.68 HPGD (0.59) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL10203414 0.67 LMNA (0.68) HPGDHSD17B10ALOX15ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1899444-B1 ASHLESS DETERGENTS AND FORMULATED LUBRICATING OIL CONTAINING SAME EXXONMOBIL RES & ENG CO (US) 2013-08-28 EP disclosed
EP-2366764-A1 Ashless detergents and formulated lubricating oil containing same ExxonMobil Research and Engineering Company (US) 2011-09-21 EP disclosed
EP-2366763-A1 Ashless detergents and formulated lubricating oil containing same ExxonMobil Research and Engineering Company (US) 2011-09-21 EP disclosed
EP-2363453-A1 Ashless detergents and formulated lubricating oil containing same ExxonMobil Research and Engineering Company (US) 2011-09-07 EP disclosed
US-7851418-B2 Ashless detergents and formulated lubricating oil containing same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-12-14 US disclosed
US-7820600-B2 Lubricant and method for improving air release using ashless detergents EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-10-26 US disclosed
CN-101184829-A Ashless detergents and formulated lubricating oils containing detergents EXXONMOBIL RES & ENG CO (US) 2008-05-21 CN disclosed
EP-1899444-A2 ASHLESS DETERGENTS AND FORMULATED LUBRICATING OIL CONTAINING SAME EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-03-19 EP disclosed
WO-2008016485-A1 LUBRICANT AND METHOD FOR IMPROVING AIR RELEASE USING ASHLESS DETERGENTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-02-07 WO disclosed
WO-2006132964-A2 ASHLESS DETERGENTS AND FORMULATED LUBRICATING OIL CONTRAINING SAME EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2006-12-14 WO disclosed
US-20060281643-A1 Lubricant and method for improving air release using ashless detergents EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2006-12-14 US disclosed
US-20060276350-A1 Ashless detergents and formulated lubricating oil containing same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2006-12-07 US disclosed