Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 16/20 | 0.50 |
| ▸ | CA1 | P00915 | 15/20 | 0.50 |
| ▸ | CA9 | Q16790 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15612900 | 0.82 | CYP1A2 (0.39) | CYP1A2CA2CA1CA9MAPT | |
| SCHEMBL15613004 | 0.80 | MAPT (0.39) | CYP1A2CA2CA1CA9MAPT | |
| SCHEMBL21623539 | 0.78 | CYP1A2 (0.84) | CYP1A2CA2CA1CA9CA12 | |
| SCHEMBL15573614 | 0.76 | CYP1A2 (0.41) | CYP1A2CA2CA1CA9MAPT | |
| SCHEMBL23677178 | 0.76 | CA1 (0.53) | CYP1A2CA2CA1CA9MAPT | |
| SCHEMBL23677279 | 0.74 | CA1 (0.57) | CYP1A2CA2CA1CA9 | |
| SCHEMBL20131060 | 0.73 | MAPT (0.48) | CYP1A2CA2CA1CA9MAPT | |
| SCHEMBL19199071 | 0.72 | CA1 (0.68) | CYP1A2CA2CA1MAPT | |
| SCHEMBL22763568 | 0.71 | CA1 (0.66) | CA2CA1MAPT | |
| SCHEMBL15613060 | 0.70 | ENPP2 (0.39) | CA2CA1CA9MAPTENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890375-B1 | SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-07-28 | — | — | EP | disclosed |