Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15651735 | 0.92 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL15652482 | 0.81 | KDR (0.46) | ALDH1A1LMNAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3387965 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3387961 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL738542 | 0.79 | HTT (0.67) | ALDH1A1LMNAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8015470 | 0.79 | ALDH1A1 (0.67) | ALDH1A1LMNAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL21292733 | 0.78 | SMN1; SMN2 (0.72) | ALDH1A1LMNAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL812698 | 0.77 | SMN1; SMN2 (0.78) | ALDH1A1LMNAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8396710 | 0.77 | SMN1; SMN2 (0.78) | ALDH1A1LMNAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL11707518 | 0.77 | SMN1; SMN2 (0.78) | ALDH1A1LMNAKMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890375-B1 | SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-07-28 | — | — | EP | disclosed |