Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387961 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2AKDM4EHTT | |
| SCHEMBL23677239 | 0.80 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2AKDM4EHTT | |
| SCHEMBL3389646 | 0.79 | LMNA (0.47) | ALDH1A1LMNAKMT2AKDM4EHTT | |
| SCHEMBL3389642 | 0.79 | LMNA (0.47) | ALDH1A1LMNAKMT2AKDM4EHTT | |
| SCHEMBL3386672 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KMT2AKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL3386668 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KMT2AKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL21240764 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2AKDM4EHTT | |
| SCHEMBL13432804 | 0.76 | ALDH1A1 (0.58) | ALDH1A1LMNAKMT2AKDM4EHTT | |
| SCHEMBL13400332 | 0.76 | LMNA (0.49) | ALDH1A1LMNAKMT2AKDM4EHTT | |
| SCHEMBL15651735 | 0.75 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ALDH1A2, MPST, CLN6 | ALDH1A1 314/4885LMNA 3498/4885KMT2A 2843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.