Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2500446 | 0.71 | KDM4E (0.50) | LMNAKDM4EALDH1A1GAAPDGFRB | |
| SCHEMBL20403565 | 0.71 | MEN1 (0.35) | GAAGPR3MEN1KMT2A | |
| SCHEMBL20508364 | 0.68 | PDGFRB (0.53) | LMNAKDM4EALDH1A1GAAPDGFRB | |
| SCHEMBL12978570 | 0.68 | LMNA (0.69) | LMNAKDM4EALDH1A1GAAPDGFRB | |
| SCHEMBL29414076 | 0.68 | LMNA (0.69) | LMNAKDM4EALDH1A1GAAPDGFRB | |
| SCHEMBL30541821 | 0.66 | PDGFRB (0.73) | LMNAKDM4EALDH1A1GAAPDGFRB | |
| SCHEMBL21971406 | 0.66 | GAA (0.47) | LMNAKDM4EALDH1A1GAAPDGFRB | |
| SCHEMBL21971409 | 0.66 | LMNA (0.44) | LMNAKDM4EALDH1A1GAAPDGFRB | |
| SCHEMBL12531910 | 0.66 | HDAC4 (0.47) | LMNAKDM4EALDH1A1GAAPDGFRB | |
| SCHEMBL12531885 | 0.66 | ALDH1A1 (0.50) | LMNAKDM4EALDH1A1GAAHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330262-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE CONTAINING SAME | LG CHEMICAL LTD (KR) | 2021-07-28 | — | — | EP | disclosed |