SCHEMBL2367896

SCHEMBL2367896

C=C(C(=O)OC(C)(C)C)C(F)(F)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196496 0.80 DGAT1 (0.33) DGAT1
SCHEMBL27516813 0.75 DGAT1 (0.30) DGAT1
SCHEMBL26103001 0.75 DGAT1 (0.36) DGAT1
SCHEMBL8398362 0.72 DGAT1 (0.37) DGAT1
SCHEMBL11365748 0.71 DGAT1 (0.33) DGAT1
SCHEMBL2146364 0.70 DGAT1 (0.36) DGAT1
Acrylic Acid SCHEMBL28051177 0.69 LMNA (0.40)
SCHEMBL2712242 0.69 DGAT1 (0.39) DGAT1
SCHEMBL2219915 0.69 DGAT1 (0.34) DGAT1
SCHEMBL78520 0.68 DGAT1 (0.46) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288496-B2 Contact lens and its manufacturing method NIPPON CONTACT LENS INC. (JP) 2012-10-16 US disclosed
US-20110237701-A1 CONTACT LENS AND ITS MANUFACTURING METHOD NIPPON CONTACT LENS INC. (JP) 2011-09-29 US disclosed
EP-2369370-A2 Contact lens and its manufacturing method Nippon Contact Lens Inc. (JP) 2011-09-28 EP disclosed