Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 2/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23679597 | 0.87 | POLB (0.47) | P2RY2P2RY4P2RY6RNASELPOLB | |
| SCHEMBL29323926 | 0.84 | RNASEL (0.58) | RNASEL | |
| SCHEMBL20324735 | 0.83 | RNASEL (0.62) | P2RY2RNASELDNPH1PRKAB2TRPM2 | |
| SCHEMBL29330554 | 0.82 | RNASEL (0.48) | P2RY2P2RY4P2RY6RNASELNT5E | |
| SCHEMBL23679813 | 0.80 | RNASEL (0.64) | RNASEL | |
| SCHEMBL30084833 | 0.79 | RNASEL (0.76) | P2RY2RNASELDNPH1PRKAB2TRPM2 | |
| SCHEMBL9951563 | 0.79 | RNASEL (0.76) | P2RY2RNASELDNPH1PRKAB2TRPM2 | |
| SCHEMBL23061368 | 0.78 | TAS1R3 (0.54) | P2RY2RNASELNT5EDNPH1PRKAB2 | |
| SCHEMBL22352118 | 0.78 | TAS1R3 (0.54) | P2RY2RNASELNT5EDNPH1PRKAB2 | |
| SCHEMBL20325272 | 0.78 | RNASEL (0.64) | P2RY2RNASELDNPH1PRKAB2TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854799-A1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |