SCHEMBL23679813

SCHEMBL23679813

Nc1ncnc2c1ncn2[C@H]1CC[C@@H](COP(=O)(O)OC2[C@H](O)C(COP(=O)(O)O)O[C@H]2n2c(=O)[nH]c3c(N)ncnc32)O1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 13/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323926 0.95 RNASEL (0.58) RNASEL
SCHEMBL23679562 0.90 RNASEL (0.49) RNASEL
SCHEMBL29330554 0.88 RNASEL (0.48) RNASEL
SCHEMBL21417134 0.86 RNASEL (0.70) RNASEL
SCHEMBL20324735 0.83 RNASEL (0.62) RNASEL
SCHEMBL29330757 0.81 RNASEL (0.53) RNASEL
SCHEMBL22352203 0.81 RNASEL (0.59) RNASEL
SCHEMBL29330468 0.81 DTYMK (0.55) RNASEL
SCHEMBL29323932 0.81 DTYMK (0.55) RNASEL
SCHEMBL22524139 0.80 RNASEL (0.58) RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3854799-A1 CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION Shanghai de Novo Pharmatech Co., Ltd. (CN) 2021-07-28 — — EP disclosed
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