Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.40 |
| ▸ | FHIT | P49789 | 2/20 | 0.38 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20763160 | 0.87 | POLB (0.54) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL22352121 | 0.87 | POLB (0.54) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL23679530 | 0.85 | POLB (0.44) | NT5EPOLBENPP1P2RY1FHIT | |
| SCHEMBL23679618 | 0.83 | NT5E (0.44) | NT5EPOLBENPP1P2RY1FHIT | |
| SCHEMBL16410980 | 0.82 | POLB (0.47) | POLBENPP1P2RY1 | |
| SCHEMBL21539899 | 0.82 | ALDH1A1 (0.49) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL22434567 | 0.82 | POLB (0.51) | POLBENPP1P2RY1P2RY2 | |
| SCHEMBL16221597 | 0.82 | POLB (0.51) | POLBENPP1P2RY1P2RY2 | |
| SCHEMBL20326935 | 0.82 | POLB (0.51) | POLBENPP1P2RY1P2RY2 | |
| SCHEMBL23679485 | 0.82 | NT5E (0.47) | NT5EPOLBENPP1P2RY1FHIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854799-A1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |