SCHEMBL21417134

SCHEMBL21417134

Nc1ncnc2c1ncn2C1OC(COP(=O)(O)O)[C@@H](O)[C@H]1OP(=O)(O)OCC1CCC(n2cnc3c(=O)[nH]cnc32)O1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 13/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20324882 0.88 RNASEL (0.56) RNASEL
SCHEMBL21540016 0.87 ALDH1A1 (0.51) RNASEL
SCHEMBL21539917 0.87 ALDH1A1 (0.51) RNASEL
SCHEMBL21539867 0.87 ALDH1A1 (0.51) RNASEL
SCHEMBL21539898 0.87 ALDH1A1 (0.51) RNASEL
SCHEMBL21540035 0.87 ALDH1A1 (0.51) RNASEL
SCHEMBL20324735 0.86 RNASEL (0.62) RNASEL
SCHEMBL23679813 0.86 RNASEL (0.64) RNASEL
SCHEMBL22352203 0.86 RNASEL (0.59) RNASEL
SCHEMBL20325277 0.86 RNASEL (0.61) RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233882-B1 FLUORINATED CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION KAYLA THERAPEUTICS (FR) 2019-10-30 — — EP disclosed
EP-3546473-A1 CYCLIC [(2',5')P(3',5')P]-DINUCLEOTIDES FOR CYTOKINE INDUCTION Kayla Therapeutics (FR) 2019-10-02 — — EP disclosed
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