SCHEMBL29330757

SCHEMBL29330757

Nc1nc2c(ncn2[C@H]2CC[C@@H](COP(=O)(O)OC3[C@H](n4c(=O)sc5c(N)ncnc54)O[C@H](COP(=O)(O)O)[C@H]3O)O2)c(=O)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 10/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20324735 0.86 RNASEL (0.62) RNASEL
SCHEMBL23679639 0.85 FUT5 (0.52) RNASEL
SCHEMBL22352203 0.84 RNASEL (0.59) RNASEL
SCHEMBL29330554 0.84 RNASEL (0.48) RNASEL
SCHEMBL22524139 0.84 RNASEL (0.58) RNASEL
SCHEMBL20324866 0.83 RNASEL (0.55) RNASEL
SCHEMBL20327562 0.82 RNASEL (0.56) RNASEL
SCHEMBL23679813 0.81 RNASEL (0.64) RNASEL
SCHEMBL20327583 0.81 STING1 (0.52) RNASEL
SCHEMBL20324890 0.81 STING1 (0.52) RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3854799-B1 CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION SHANGHAI DE NOVO PHARMATECH CO LTD (CN) 2024-07-17 — — EP disclosed
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