SCHEMBL2368071

SCHEMBL2368071

C=Cc1ccccc1C(C)[Si](O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)(O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2368287 0.92 ALDH1A1 (0.33) ALDH1A1
SCHEMBL2367617 0.88 ALDH1A1 (0.31) ALDH1A1
SCHEMBL886909 0.79 ALDH1A1 (0.35) ALDH1A1
SCHEMBL2367920 0.78 ALDH1A1 (0.30) ALDH1A1
SCHEMBL8383509 0.77 ALDH1A1 (0.39) ALDH1A1
SCHEMBL3305911 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL1269643 0.74 ALDH1A1 (0.34) ALDH1A1
SCHEMBL5487860 0.72 ALDH1A1 (0.42) ALDH1A1
SCHEMBL373084 0.71 ALDH1A1 (0.34) ALDH1A1
SCHEMBL373779 0.71 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288496-B2 Contact lens and its manufacturing method NIPPON CONTACT LENS INC. (JP) 2012-10-16 US disclosed
US-20110237701-A1 CONTACT LENS AND ITS MANUFACTURING METHOD NIPPON CONTACT LENS INC. (JP) 2011-09-29 US disclosed
EP-2369370-A2 Contact lens and its manufacturing method Nippon Contact Lens Inc. (JP) 2011-09-28 EP disclosed