SCHEMBL373779

SCHEMBL373779

C=Cc1ccccc1[Si](C)(C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL373739 0.91 ALDH1A1 (0.38) ALDH1A1
SCHEMBL373084 0.86 ALDH1A1 (0.34) ALDH1A1
SCHEMBL373306 0.86 ALDH1A1 (0.34) ALDH1A1
SCHEMBL373401 0.85 ALDH1A1 (0.33) ALDH1A1
SCHEMBL372833 0.85 ALDH1A1 (0.33) ALDH1A1
SCHEMBL373818 0.85 ALDH1A1 (0.33) ALDH1A1
SCHEMBL373565 0.85 ALDH1A1 (0.33) ALDH1A1
SCHEMBL373533 0.85 ALDH1A1 (0.33) ALDH1A1
SCHEMBL373727 0.85 ALDH1A1 (0.33) ALDH1A1
SCHEMBL372504 0.85 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP claimed
US-12428390-B2 Chromene compound and photochromic optical article TOKUYAMA CORPORATION (JP) 2025-09-30 US disclosed
EP-3822296-B1 POLYMER MATERIAL MENICON CO LTD (JP) 2025-09-10 EP disclosed
US-20250115701-A1 POLYMER MATERIAL MENICON CO., LTD. (JP) 2025-04-10 US disclosed
US-12209154-B2 Polymer material MENICON CO., LTD. (JP) 2025-01-28 US disclosed
EP-3995493-B1 CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE TOKUYAMA CORP (JP) 2024-07-03 EP disclosed
US-20240026145-A1 OPHTHALMIC LENS MENICON CO., LTD. (JP) 2024-01-25 US disclosed
EP-4206797-A1 OPHTHALMIC LENS Menicon Co., Ltd. (JP) 2023-07-05 EP disclosed
EP-2657304-B1 AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS MENICON CO LTD (JP) 2022-12-07 EP disclosed
US-20220244428-A1 OPHTHALMIC MEDICAL INSTRUMENT INCLUDING PHOTOCHROMIC POLYMER AND PRODUCTION METHOD FOR OPHTHALMIC MEDICAL INSTRUMENT MENICON CO., LTD. (JP) 2022-08-04 US disclosed
EP-0890636-A1 Culture vessel Menicon Co., Ltd. (JP) 1999-01-13 EP disclosed
US-5741830-A COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE MENICON CO., LTD. (JP) 1998-04-21 US disclosed
EP-0584764-B1 Ocular lens material MENICON CO LTD (JP) 1997-03-26 EP disclosed
EP-0729041-A2 Water-Absorptive soft contact lens Menicon Co., Ltd. (JP) 1996-08-28 EP disclosed
US-5416180-A Fluorine containing (meth)acrylate polymers MENICON CO., LTD. (JP) 1995-05-16 US disclosed
US-5416132-A Acrylamide modified acrylate modified polysiloxanes MENICON CO., LTD. (JP) 1995-05-16 US disclosed
US-5346946-A Polysiloxane macromonomer MENICON CO., LTD (JP) 1994-09-13 US disclosed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP disclosed
EP-0584826-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP disclosed
EP-0584764-A1 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428390-B2 Chromene compound and photochromic optical article CRY1, CRY2, RAD51 ALDH1A1 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.