SCHEMBL5487860

SCHEMBL5487860

C=Cc1ccccc1C(C)[Si](Cl)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
CRHR1 P34998 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8383509 0.82 ALDH1A1 (0.39) ALDH1A1
SCHEMBL1507296 0.79 ALDH1A1 (0.48) ALDH1A1CRHR1
SCHEMBL8713730 0.79 GABRA1 (0.39) ALDH1A1
SCHEMBL886909 0.78 ALDH1A1 (0.35) ALDH1A1
SCHEMBL29364896 0.77 ALDH1A1 (0.44) ALDH1A1
SCHEMBL50011 0.77 ALDH1A1 (0.44) ALDH1A1
SCHEMBL29717597 0.77 GABRA1 (0.44) ALDH1A1
SCHEMBL6281523 0.77 ALDH1A1 (0.44) ALDH1A1
SCHEMBL56243 0.77 GABRA1 (0.44) ALDH1A1
SCHEMBL1269643 0.77 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed