SCHEMBL2368090

SCHEMBL2368090

CC(C)CC(NC(=O)Cc1ccccc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.64
PSMB5 P28074 1/20 0.64
MME P08473 2/20 0.61
CTSL P07711 1/20 0.61
LTA4H P09960 1/20 0.58
ACE P12821 1/20 0.58
POLB P06746 2/20 0.56
FOLH1 Q04609 1/20 0.56
CNR2 P34972 2/20 0.55
NTSR1 P30989 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2368096 1.00 PSMB8 (0.64) PSMB8PSMB5MMECTSLLTA4H
SCHEMBL15251753 1.00 PSMB8 (0.64) PSMB8PSMB5MMECTSLLTA4H
SCHEMBL9830820 0.90 MME (0.66) PSMB5MMECTSLLTA4HACE
SCHEMBL9830825 0.90 MME (0.66) PSMB5MMECTSLLTA4HACE
SCHEMBL24831957 0.88 ALDH1A1 (0.64) PSMB8PSMB5CTSLFOLH1CNR2
SCHEMBL9829825 0.88 FOLH1 (0.68) PSMB8PSMB5MMECTSLACE
SCHEMBL9829831 0.88 FOLH1 (0.68) PSMB8PSMB5MMECTSLACE
SCHEMBL6941568 0.88 PSMB8 (0.61) PSMB8PSMB5CTSLPOLBCNR2
SCHEMBL9831107 0.87 CNR2 (0.57) PSMB8PSMB5CTSLPOLBFOLH1
SCHEMBL9831110 0.87 CNR2 (0.57) PSMB8PSMB5CTSLPOLBFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109182200-B Lysinibacillus fusiformis ZJB-17006 and application thereof 浙江工业大学 2020-10-09 CN claimed
CN-109321493-B B-lysine-resistant bacillus ZJB-17007 and application thereof 浙江工业大学 2020-10-02 CN claimed
CN-109321495-B Clinkerwell ZJB-17005 and application thereof 浙江工业大学 2020-08-21 CN claimed
CN-109321491-B Xiangfang enterobacter ZJB-17001 and application thereof 浙江工业大学 2020-08-21 CN claimed
CN-109321490-B Enterobacter aerogenes ZJB-17003 and application thereof 浙江工业大学 2020-08-21 CN claimed
CN-109321492-B Non-decarboxylation lechler bacterium ZJB-17008 and application thereof 浙江工业大学 2020-08-21 CN claimed
CN-109321497-B Lysine-elongated bacillus ZJB-17009 and application thereof 浙江工业大学 2020-07-28 CN claimed
CN-109182201-B Enterobacter hesheng biological I type ZJB-17002 and application thereof 浙江工业大学 2020-06-23 CN claimed
CN-109321496-B Citrobacter freundii ZJB-17010 and application thereof 浙江工业大学 2020-06-23 CN claimed
CN-109321494-B Kluyveromyces intermedia ZJB-17004 and application thereof 浙江工业大学 2020-06-23 CN claimed
CN-109321497-A Long lysine bacillus ZJB-17009 and its application 浙江工业大学 2019-02-12 CN claimed
CN-109321495-A Kluyvera cryocrescens ZJB-17005 and its application 浙江工业大学 2019-02-12 CN claimed
CN-109321494-A Intermediate gram Lyu Wall bacterium ZJB-17004 and its application 浙江工业大学 2019-02-12 CN claimed
CN-109321490-A Clostridium perfringen ZJB-17003 and its application 浙江工业大学 2019-02-12 CN claimed
CN-109321491-A Xiangfang enterobacteria ZJB-17001 and its application 浙江工业大学 2019-02-12 CN claimed
CN-109182201-A Enterobacter amnigenus I type ZJB-17002 of biology and its application 浙江工业大学 2019-01-11 CN claimed
CN-109182200-A Spindle lysine bacillus ZJB-17006 and its application 浙江工业大学 2019-01-11 CN claimed
CN-101368199-A Method for preparing D-aminophenol with immobilization penicillin acylated enzyme catalysis UNIV CHONGQING POSTS & TELECOM (CN) 2009-02-18 CN claimed
EP-0951464-B1 N-(ARYL/HETEROARYLACETYL) AMINO ACID ESTERS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS ELAN PHARM INC (US) 2005-05-11 EP claimed
CN-1237960-A N (aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and method for inhibiting 'beta'-amyloid peptide release and/or its synthesis by use of such compounds YEELAN PHARMACEUTICAL CORP (US) 1999-12-08 CN claimed