Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831110 | 1.00 | CNR2 (0.57) | CNR2KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL2368096 | 0.87 | PSMB8 (0.64) | CNR2PSMB8PSMB5POLBFOLH1 | |
| SCHEMBL2368090 | 0.87 | PSMB8 (0.64) | CNR2PSMB8PSMB5POLBFOLH1 | |
| SCHEMBL15251753 | 0.87 | PSMB8 (0.64) | CNR2PSMB8PSMB5POLBFOLH1 | |
| SCHEMBL29071697 | 0.87 | CNR2 (0.54) | CNR2KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL28045762 | 0.87 | CNR2 (0.48) | CNR2PSMB8PSMB5NAALAD2POLB | |
| SCHEMBL10504767 | 0.84 | ITGB3 (0.65) | CNR2PSMB8PSMB5NAALAD2CTSL | |
| SCHEMBL6137652 | 0.84 | CNR2 (0.59) | CNR2KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL6137656 | 0.84 | CNR2 (0.59) | CNR2KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL4144665 | 0.84 | ITGB3 (0.65) | CNR2PSMB8PSMB5NAALAD2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |