Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23680934 | 0.79 | SLC6A2 (0.42) | MAPTSLC6A2MAOATRPV1KMT2A | |
| Hydrochloric Acid SCHEMBL22436644 | 0.78 | SLC6A2 (0.41) | MAPTSLC6A2MAOATRPV1HTT | |
| Hydrochloric Acid SCHEMBL22436645 | 0.78 | SLC6A2 (0.41) | MAPTSLC6A2MAOATRPV1HTT | |
| SCHEMBL25343021 | 0.76 | CACNA1B (0.46) | KDM4EHPGDMAPTGLAGAA | |
| SCHEMBL29501742 | 0.74 | HTT (0.35) | HPGDMAPTGAASLC6A2TRPV1 | |
| SCHEMBL29047772 | 0.74 | HTT (0.35) | HPGDMAPTGAASLC6A2TRPV1 | |
| SCHEMBL28829894 | 0.74 | SLC6A2 (0.47) | MAPTKDM1ASLC6A2MAOATRPV1 | |
| SCHEMBL24298844 | 0.72 | HDAC1 (0.45) | KDM4EHPGDMAPTGLAGAA | |
| SCHEMBL24298843 | 0.72 | HDAC1 (0.45) | KDM4EHPGDMAPTGLAGAA | |
| SCHEMBL17902291 | 0.71 | NR1H4 (0.42) | KDM4EHPGDMAPTGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344279-B | Microbiocidal picolinamide derivatives | 先正达参股股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| EP-3710429-B1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-05 | — | — | EP | disclosed |
| US-11291205-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-05 | — | — | US | disclosed |
| US-20210227826-A1 | Microbiocidal Picolinamide Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-07-29 | — | — | US | disclosed |
| CN-111344279-A | Microbicidal picolinamide derivatives | 先正达参股股份有限公司 | 2020-06-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11291205-B2 | Microbiocidal picolinamide derivatives | CASP2, CASP1, MSR1 | KDM4E 4007/4885HPGD 754/4885MAPT 3159/4885 |
| US-20210227826-A1 | Microbiocidal Picolinamide Derivatives | CASP2, CASP1, MSR1 | KDM4E 4007/4885HPGD 754/4885MAPT 3159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.