Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249889 | 0.81 | KDM1A (0.42) | LMNAKDM1A | |
| SCHEMBL23680934 | 0.81 | SLC6A2 (0.42) | SLC6A2TRPV1HTTPOLBL3MBTL1 | |
| SCHEMBL24658450 | 0.80 | KDM1A (0.44) | SLC6A2LMNAMAOAKDM1A | |
| Hydrochloric Acid SCHEMBL22436645 | 0.80 | SLC6A2 (0.41) | SLC6A2TRPV1HTTPOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL22436644 | 0.80 | SLC6A2 (0.41) | SLC6A2TRPV1HTTPOLBL3MBTL1 | |
| SCHEMBL3170686 | 0.80 | SMN1; SMN2 (0.50) | POLBMAPTTDP1SMN1; SMN2KDM1A | |
| SCHEMBL6249011 | 0.79 | GABRA1 (0.52) | SLC6A2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL23680936 | 0.74 | KDM4E (0.40) | SLC6A2TRPV1HTTPOLBL3MBTL1 | |
| SCHEMBL301271 | 0.71 | FFAR1 (0.55) | SLC6A2TRPV1HTTPOLBL3MBTL1 | |
| SCHEMBL9820868 | 0.71 | TRPV1 (0.50) | SLC6A2TRPV1HTTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003110-B | Aryl beta-aminoketone compound and preparation method thereof | 南京工业大学 | 2022-09-06 | — | — | CN | claimed |