Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23680976 | 0.86 | ALDH1A1 (0.56) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL19580347 | 0.78 | ALDH1A1 (0.71) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL2281070 | 0.77 | CYP2C19 (0.70) | ALDH1A1MAPTHTTAKR1C3KMT2A | |
| SCHEMBL23680979 | 0.76 | MAPT (0.47) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL13543488 | 0.74 | ALDH1A1 (0.69) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL28954097 | 0.68 | DHODH (0.47) | HRH3LOXL2 | |
| SCHEMBL13545200 | 0.68 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL27893517 | 0.68 | ALDH1A1 (0.67) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL28210660 | 0.67 | DHODH (0.46) | HRH3LOXL2 | |
| SCHEMBL13543278 | 0.67 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021150871-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS WITH RIPK1/RIPK3 INHIBITORS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-07-29 | — | — | WO | disclosed |