SCHEMBL23682703

SCHEMBL23682703

O=C(c1cccc(Br)c1)N1CCC(N2CCC2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL3 Q96JM7 16/20 1.00
▸ L3MBTL1 Q9Y468 12/20 0.95
▸ L3MBTL4 Q8NA19 2/20 0.95
▸ MBTD1 Q05BQ5 3/20 0.92
▸ HPGD P15428 1/20 0.68
▸ ALDH1A1 P00352 1/20 0.68
▸ TP53 P04637 1/20 0.68
▸ TDP1 Q9NUW8 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19730382 0.97 L3MBTL3 (1.00) L3MBTL3L3MBTL1L3MBTL4MBTD1HPGD
Hydrochloric Acid SCHEMBL30014223 0.96 L3MBTL3 (0.97) L3MBTL3L3MBTL1L3MBTL4MBTD1HPGD
SCHEMBL23682668 0.96 MBTD1 (1.00) L3MBTL3L3MBTL1L3MBTL4MBTD1HPGD
SCHEMBL23682645 0.93 L3MBTL3 (1.00) L3MBTL3L3MBTL1L3MBTL4MBTD1HPGD
SCHEMBL23682910 0.89 L3MBTL3 (0.85) L3MBTL3L3MBTL1L3MBTL4MBTD1HPGD
SCHEMBL23682681 0.89 L3MBTL3 (0.80) L3MBTL3L3MBTL1L3MBTL4MBTD1HPGD
SCHEMBL23682884 0.88 L3MBTL3 (1.00) L3MBTL3L3MBTL1L3MBTL4MBTD1HPGD
SCHEMBL23682802 0.87 L3MBTL3 (1.00) L3MBTL3L3MBTL1L3MBTL4MBTD1TDP1
SCHEMBL265991 0.82 HPGD (1.00) L3MBTL3L3MBTL1L3MBTL4MBTD1HPGD
SCHEMBL23682749 0.82 L3MBTL3 (1.00) L3MBTL3L3MBTL1L3MBTL4MBTD1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285573-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2023-09-14 — — US disclosed
US-20230285573-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2023-09-14 — — US disclosed
US-20230050819-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2023-02-16 — — US disclosed
US-20210283265-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-09-16 — — US disclosed
US-20210284629-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-09-16 — — US disclosed
US-20210238226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-08-05 — — US disclosed
US-20210228723-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-07-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE ATXN2L, ATXN2, ATXN10 L3MBTL3 3097/4885L3MBTL1 3195/4885L3MBTL4 3486/4885
US-20230285573-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE NEDD4, CBL, UBQLN2 L3MBTL3 518/4885L3MBTL1 228/4885L3MBTL4 445/4885
US-20210283265-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE NEDD4, CBL, UBQLN2 L3MBTL3 518/4885L3MBTL1 228/4885L3MBTL4 445/4885
US-20230050819-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE CYFIP2, TPX2, ATXN2 L3MBTL3 1221/4885L3MBTL1 737/4885L3MBTL4 1173/4885
US-20210228723-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE ZFX, F13B, GRN L3MBTL3 1368/4885L3MBTL1 718/4885L3MBTL4 1297/4885
US-20210284629-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE NEDD4, UBQLN2, UBTF L3MBTL3 372/4885L3MBTL1 173/4885L3MBTL4 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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