Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362620 | 0.86 | FAAH (0.47) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL2701579 | 0.85 | GAA (0.60) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL2521741 | 0.85 | MGAM (0.46) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL28875528 | 0.83 | FAAH (0.53) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL27853441 | 0.83 | FAAH (0.53) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL28136427 | 0.83 | FAAH (0.53) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL28021506 | 0.83 | FAAH (0.53) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL28040109 | 0.82 | — | — | |
| Water SCHEMBL2703341 | 0.82 | GAA (0.57) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL649327 | 0.80 | MGAM (0.55) | GAAMGAMSIMGAM2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995584-B | Preparation method of oxalagrill intermediate | 常州工学院 | 2022-03-29 | — | — | CN | disclosed |
| CN-113372292-A | Preparation method of ceftazidime side chain acid | 山东昌邑四方医药化工有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-111995584-A | Preparation method of oxalagrill intermediate | 常州工学院 | 2020-11-27 | — | — | CN | disclosed |
| CN-105837635-A | Preparation method of minodronic acid for treating osteoporosis | 青岛辰达生物科技有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-103351322-B | A kind of synthetic method of oxiracetam | GUANG'AN KINGDAY PHARM & CHEMICAL CO., LTD. (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-102939290-B | 2,3-dihydro-1H-indenes-1-base-2,7-diaza spiro [3.5] nonane derivatives and as the antagonist of growth hormone-releasing peptide acceptor or the purposes of inverse agonist | PFIZER INC. (US) | 2015-09-16 | — | — | CN | disclosed |
| CN-103201260-B | Drug derivatives | REDX PHARMA LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-104334193-A | Use of ghrelin receptor inverse agonists or antagonists for the treatment of sleep disorders | PFIZER | 2015-02-04 | — | — | CN | disclosed |
| CN-103534257-A | Pyrrolo [2, 3 -d] pyrimidine derivatives as inhibitors of tropomyosin- related kinases | PFIZER | 2014-01-22 | — | — | CN | disclosed |
| CN-103351322-A | Synthetic method of oxiracetam | GUANG AN KINGDAY PHARM & CHEMICAL CO LTD | 2013-10-16 | — | — | CN | disclosed |
| EP-2367825-A1 | Fused imidazole carboxamides as trpv3 modulators | Glenmark Pharmaceuticals S.A. (CH) | 2011-09-28 | — | — | EP | disclosed |
| CN-102002016-A | Improvement method for synthesizing febuxostat | BEIJING MEIDI KANGXIN MEDICAL TECHNOLOGY CO LTD | 2011-04-06 | — | — | CN | disclosed |
| WO-2010070452-A1 | FUSED IMIDAZOLE CARBOXAMIDES AS TRPV3 MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-06-24 | — | — | WO | disclosed |
| US-20100152192-A1 | FUSED IMIDAZOLE CARBOXAMIDES AS TRPV3 MODULATORS | GLENMARK PHARMACEUTICALS S.A (CH) | 2010-06-17 | — | — | US | disclosed |
| EP-0371492-B1 | Process for the preparation of 1,4-dihydropyridine derivatives | NISSHIN FLOUR MILLING CO (JP) | 1995-06-21 | — | — | EP | disclosed |
| US-4994461-A | Vasodilators; treating cardiovascular disorders | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1991-02-19 | — | — | US | disclosed |
| EP-0371492-A2 | Process for the preparation of 1,4-dihydropyridine derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4472411-A | 1,4-Dihydropyridine derivatives and use as vasodilators | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0092936-A1 | 1,4-Dihydropyridine derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-11-02 | — | — | EP | disclosed |
| US-4146509-A | ORGANIC AMMONIUM COMPOUNDS USED AS POLYMERIZATION CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152192-A1 | FUSED IMIDAZOLE CARBOXAMIDES AS TRPV3 MODULATORS | TRPV3, TRPV1, TRPV2 | GAA 3758/4885MGAM 4557/4885SI 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.