Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419807 | 0.89 | ALDH1A1 (0.66) | PAMALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL231282 | 0.86 | TSHR (0.61) | PAMALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL6416798 | 0.85 | ALDH1A1 (0.61) | PAMALDH1A1MAPK1L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL7053203 | 0.84 | TSHR (0.58) | PAMALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL4226282 | 0.84 | TSHR (0.58) | PAMALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL52219 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL3439041 | 0.83 | ALDH1A1 (0.63) | PAMALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL11632800 | 0.82 | TSHR (0.56) | PAMALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL11907176 | 0.82 | ALDH1A1 (0.58) | PAMALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL5446199 | 0.82 | ALDH1A1 (0.46) | PAMALDH1A1MAPK1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230205-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230205-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | SERPINB1, KLKB1, MPO | PAM 1576/4885ALDH1A1 833/4885MAPK1 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.