Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931626 | 1.00 | LMNA (0.59) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11677845 | 1.00 | LMNA (0.59) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL469037 | 0.98 | LMNA (0.56) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3590458 | 0.90 | ALDH1A1 (0.46) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10182181 | 0.83 | LMNA (0.68) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10180298 | 0.81 | LMNA (0.65) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL19127214 | 0.81 | SMN1; SMN2 (0.50) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30772120 | 0.81 | LMNA (0.40) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6268570 | 0.80 | LMNA (0.64) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23686012 | 0.80 | LMNA (0.59) | LMNAHTTSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210227827-A1 | METHOD FOR PATHOGENS, MICROORGANISMS, AND PARASITES INACTIVATION | NEW YORK BLOOD CENTER, INC. | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210227827-A1 | METHOD FOR PATHOGENS, MICROORGANISMS, AND PARASITES INACTIVATION | MGMT, O60361, SAMHD1 | LMNA 1374/4885HTT 1589/4885SMN1; SMN2 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.