Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23686935 | 0.97 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2RECQLLMNA | |
| SCHEMBL1952517 | 0.90 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2RECQLLMNA | |
| SCHEMBL1952587 | 0.89 | LMNA (0.55) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1952436 | 0.84 | MGLL (0.62) | NPC1RAB9ASMN1; SMN2RECQLLMNA | |
| SCHEMBL25120445 | 0.82 | LMNA (0.48) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1021824 | 0.82 | LMNA (0.60) | NPC1RAB9ASMN1; SMN2RECQLLMNA | |
| SCHEMBL10595749 | 0.78 | LMNA (0.65) | NPC1RAB9ASMN1; SMN2RECQLLMNA | |
| SCHEMBL1023753 | 0.77 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11766069 | 0.77 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17346690 | 0.76 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021148562-A1 | WATERBORNE CROSSLINKER COMPOSITION | COVESTRO (NETHERLANDS) B.V. (NL) | 2021-07-29 | — | — | WO | disclosed |