SCHEMBL2369290

SCHEMBL2369290

NCCCCCCCn1ccnc1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 14/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5988937 1.00 TBXAS1 (0.79) TBXAS1
SCHEMBL2369806 1.00 TBXAS1 (0.79) TBXAS1
SCHEMBL7276173 1.00 TBXAS1 (0.79) TBXAS1
SCHEMBL3172850 1.00 TBXAS1 (0.79) TBXAS1
SCHEMBL3173441 1.00 TBXAS1 (0.79) TBXAS1
Hydrochloric Acid SCHEMBL3530240 0.98 TBXAS1 (0.76) TBXAS1
SCHEMBL139976 0.98 TBXAS1 (0.75) TBXAS1
Hydrochloric Acid SCHEMBL7276913 0.96 TBXAS1 (0.72) TBXAS1
Bromide SCHEMBL18941395 0.96 TBXAS1 (0.72) TBXAS1
SCHEMBL9253280 0.91 TBXAS1 (0.71) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116718657-A Preparation method of glucose biological sensing membrane and glucose biological sensor 深圳木芯科技有限公司 2023-09-08 CN claimed
CN-116718657-A Preparation method of glucose biological sensing membrane and glucose biological sensor 深圳木芯科技有限公司 2023-09-08 CN disclosed
US-20190169342-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA, INC. 2019-06-06 US disclosed
US-20190169342-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA, INC. 2019-06-06 US disclosed
EP-3130343-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS Relypsa, Inc. (US) 2017-02-15 EP disclosed
EP-3130343-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS Relypsa, Inc. (US) 2017-02-15 EP disclosed
EP-2538947-B1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA INC (US) 2016-08-17 EP disclosed
EP-2538947-B1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA INC (US) 2016-08-17 EP disclosed
US-20130189215-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA, INC. (US) 2013-07-25 US disclosed
US-20130189215-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA, INC. (US) 2013-07-25 US disclosed
EP-0230035-B1 Omega-[(hetero)alkyl]benz[cd]indol-2-amines AMERICAN CYANAMID CO (US) 1994-10-12 EP disclosed
US-5081131-A Omega-((hetero)alkyl)benz(cd)-indol-2-amines AMERICAN CYANAMID COMPANY (US) 1992-01-14 US disclosed
EP-0230035-A2 Omega-[(hetero)alkyl]benz[cd]indol-2-amines AMERICAN CYANAMID COMPANY (US) 1987-07-29 EP disclosed
US-4619941-A N-[(1H-imidazol-1-yl)alkyl]-1H-indolecarboxamides useful as thromboxane synthetase inhibitors and antihypertensive agents AMERICAN CYANAMID COMPANY (US) 1986-10-28 US disclosed
US-4576957-A HYPOTENSIVE AMERICAN CYANAMID COMPANY (US) 1986-03-18 US disclosed
US-4568687-A THROMBOXANE SYNTHETASE TNZYME INHIBITORS; HYPOTENSIVE AGENTS, CARDIOTONIC AGENTS AMERICAN CYANAMID COMPANY (US) 1986-02-04 US disclosed
US-4555519-A Thromboxane synthetase enzyme inhibiting N-[(1H-imidazol-1-yl) and (1H-1,2,4-triazol-1-yl)alkyl]pyridinecarboxamides AMERICAN CYANAMID COMPANY (US) 1985-11-26 US disclosed
US-4489089-A INHIBITION OF THE ENZYME THROMBOXANE SYNTHETASE AMERICAN CYANAMID COMPANY (US) 1984-12-18 US disclosed
EP-0127727-A2 Substituted N-(omega-(1H-imidazol-1-yl)alkyl)) amides AMERICAN CYANAMID COMPANY (US) 1984-12-12 EP disclosed
US-4320134-A HYPOTENSIVE, ANTIASTHMATIC AND ANTIINFLAMMATORY AGENTS ONO PHARMACEUTICAL CO., LTD. (JP) 1982-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130189215-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS NR1H4, SLC10A2, ITCH TBXAS1 2184/4885
US-20190169342-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS NR1H4, SLC10A2, ITCH TBXAS1 2184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.