Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788978 | 0.84 | STAT3 (0.37) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL5789263 | 0.74 | HSD17B10 (0.40) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL5791821 | 0.73 | ALDH1A1 (0.39) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL6358001 | 0.73 | ALDH1A1 (0.36) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL3383720 | 0.66 | SMN1; SMN2 (0.60) | MAPTLMNAL3MBTL1HTTPOLB | |
| SCHEMBL5040863 | 0.64 | THRB (0.55) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL29166060 | 0.63 | HSP90AA1 (0.46) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL577663 | 0.62 | MAPT (0.44) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL1285054 | 0.62 | APP (0.60) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL11665288 | 0.62 | PTPRC (0.50) | MAPTMEN1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022076-B2 | Thieno[2,3-d]pyrimidine derivatives as potassium channel modulators; antiarrhythmia agents | XENTION LIMITED (GB) | 2011-09-20 | — | — | US | disclosed |